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643 Main Street, 
Lewiston, ME 04240

$337,500


4

Beds


3

Baths


1,961

Sq Ft


Single Family


Virtual Tour

Active

Last updated:

August 24, 2026, 10:27 AM

MLS#

1668737

Source:

ME MREIS

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About This Home

643 Main Street

Whether you're looking for a place to live, operate a business, or combine both under one roof, 643 Main Street in Lewiston offers the flexibility to make it happen. The second floor features up to four potential bedrooms, while the first floor provides a large open living area that can be adapted to a variety of residential or commercial uses. A sunroom overlooking the side parking area adds additional usable space and natural light. The property includes a full basement with a garage bay and half bathroom, offering excellent storage, workshop space, or additional functionality. Recent improvements include a new boiler, new roof, new siding, and updated electrical service, helping reduce future maintenance concerns and adding peace of mind. With its highly visible Main Street location, flexible layout, and numerous potential uses, this property presents a unique opportunity for entrepreneurs, investors, or homeowners looking for a property that can adapt to their needs. See MLS#1673389

Home Facts

Single Family

3 Baths

4 Bedrooms

Built in 1925

Price Summary

337,500

$172 per Sq. Ft.

MLS #:

1668737

Last Updated:

August 24, 2026, 10:27 AM


Rooms & Interior

Bedrooms

Total Bedrooms:

4

Bathrooms

Total Bathrooms:

3

Full Bathrooms:

1


Structure

Structure

Architectural Style:

Colonial

Building Area:

1,961 Sq. Ft.

Year Built:

1925


Lot

Lot Size (Sq. Ft):

25,264


Finances & Disclosures

Finances

Price:

$337,500

Price per Sq. Ft:

$172 per Sq. Ft.

643 Main Street
MLS Logo
MREIS Multiple Listing Service™ systemListing data is derived in whole or in part from the Maine IDX & is for consumers' personal, noncommercial use only. Dimensions are approximate and not guaranteed. All data should be independently verified. © 2026 Maine Real Estate Information System, Inc. All Rights Reserved

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Contact an Agent

Yes, I would like more information. Please use and/or share my information with a Coldwell Banker ® affiliated agent to contact me about my real estate needs. By clicking Contact, I request to be contacted by phone or text message and consent to being contacted by automated means. I understand that my consent to receive calls or texts is not a condition of purchasing any property, goods, or services. Alternatively, I understand that I can access real estate services by email or I can contact the agent myself.

If a Coldwell Banker affiliated agent is not available in the area where I need assistance, I agree to be contacted by a real estate agent affiliated with another brand owned or licensed by Anywhere Real Estate (BHGRE®, CENTURY 21®, Corcoran®, ERA®, or Sotheby's International Realty®). I acknowledge that I have read and agree to the terms of use and privacy notice.