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2221 Cherokee Blvd, 
Knoxville, TN 37919

$2,300,000


5

Beds


6

Baths


5,390

Sq Ft


Single Family

Active

Listed by

Billy Houston

Billy Houston Group, Realty Executives

865-577-7653

Last updated:

August 30, 2025, 02:35 PM

MLS#

1305008

Source:

TN KAAR

About This Home

2221 Cherokee Blvd

Welcome to this one-of-a-kind Sequoyah Hills classic—where timeless charm meets thoughtful modern updates. Originally built in 1930, this beautifully renovated home retains all the character of its era while offering the comfort and style that today's lifestyle demands. Nestled in the heart of picturesque Sequoyah Hills, you'll enjoy convenient access to Cherokee Boulevard's scenic trails, Sequoyah Park, and Knoxville's expansive greenway system—all just minutes from downtown and the University of Tennessee. From the moment you arrive, you'll be captivated by the clinker brick exterior, elegant copper gutters, and slate roofs. Inside, original woodwork and arched doorways blend seamlessly with fabulous new lighting and contemporary design elements. The gourmet kitchen features a spacious central island and gas cooktop, opening effortlessly to warm, inviting dining and living areas anchored by a cozy gas fireplace and a large picture window. With 5 bedrooms and 5.5 baths, this home offers exceptional flexibility—including a perfect office or guest suite with private bath, plus separate guest quarters above the garage with its own entrance. This is more than a home—it's a rare opportunity to own a piece of Knoxville history with all the benefits of modern living. Don't miss this truly special property.

Home Facts

Single Family

6 Baths

5 Bedrooms

Built in 1930

Price Summary

2,300,000

$426 per Sq. Ft.

MLS #:

1305008

Last Updated:

August 30, 2025, 02:35 PM

Added:

2 month(s) ago


Rooms & Interior

Bedrooms

Total Bedrooms:

5

Bathrooms

Total Bathrooms:

6

Full Bathrooms:

5

Interior

Living Area:

5,390 Sq. Ft.


Structure

Structure

Architectural Style:

Traditional, Tudor

Building Area:

5,390 Sq. Ft.

Year Built:

1930


Lot

Lot Size (Sq. Ft):

35,283


Finances & Disclosures

Finances

Price:

$2,300,000

Price per Sq. Ft:

$426 per Sq. Ft.

Source:TN KAAR
The information being provided by Knoxville Area Association of REALTORS is for the consumer’s personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information is deemed reliable but not guaranteed and should therefore be independently verified. © 2025 Knoxville Area Association of REALTORS All rights reserved.

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By clicking Contact I agree a Coldwell Banker Agent may contact me by phone or text message including by automated means and prerecorded messages about real estate services, and that I can access real estate services without providing my phone number. I acknowledge that I have read and agree to the Terms of Use and Privacy Notice.