Room to Move. This expansive full-floor loft of nearly 5,000 square feet brings together classic Tribeca architecture and a clean, contemporary interior. A key-locked elevator opens directly into a generous 50'-wide living and dining space, framed by eight oversized windows and a wood-burning fireplace. High ceilings, multiple seating areas, and iconic cast-iron views define the room as a natural setting for both everyday living and larger gatherings. At one end, a glass-enclosed study serves equally well as a library, media room, or potential fourth bedroom with convenient bath access. The kitchen is thoughtfully scaled for cooking and entertaining, centered around a large marble island with counter seating and ample work surfaces. Viking and Sub-Zero appliances, two Miele dishwashers, and substantial storage are complemented by a bar with dual wine storage and a separate dining area that comfortably accommodates larger groups. A nearby den and additional sitting areas offer more relaxed spaces, while an enclosed library provides a quiet workspace set apart from the main living areas. The private wing is set apart from the entertaining spaces and begins with a well-proportioned primary suite. The bedroom allows for a seating area and benefits from south-facing light, along with two large walk-in closets. The en-suite bath is finished in marble and includes a glass-enclosed shower, double vanity, private water closet, and a freestanding soaking tub positioned beside an interior window that draws in natural light. Two additional bedrooms, each with en-suite baths and generous closets, share the same approximately 11-foot ceilings found throughout the loft. Completed in 2001 as a condominium conversion by Platt Byard Dovell, 45 Walker Street is a late 19th-century, seven-story building with just six residential lofts. Its scale ensures a quiet, private atmosphere with minimal common circulation. Amenities include a virtual doorman with video security and two large private storage units that transfer with the apartment. Pets and pied-à-terre ownership are permitted, offering a practical option for both primary and secondary residence buyers seeking volume, discretion, and an established Tribeca address.