Opportunities in South Dover like this do not come along often. Welcome to 33 Piscataqua Road, a spacious 4–5-bedroom home set on a full acre in one of Dover’s most sought-after locations - just moments from the highly coveted Garrison School, Pease Tradeport, the UNH campus, downtown Portsmouth, and favorite Seacoast destinations. For buyers seeking the right combination of space, privacy, schools, and convenience, this home is a must see. The home offers a flexible and functional layout with generous living areas designed to accommodate everything from busy everyday life to holiday gatherings and entertaining. A welcoming fireplace anchors the main living space, while the kitchen, dining, and adjoining rooms provide an easy flow and plenty of versatility for gathering, working from home, homework, or simply relaxing at the end of the day. A convenient half bath completes the first floor. Upstairs are four comfortable bedrooms and two full baths, offering excellent flexibility for family, guests, office space, or a playroom. A full walk-up attic provides even more potential and could be finished to create additional living space, a studio, bonus room, or private retreat. The lower level is partially finished with a mudroom area and a bedroom/bonus room that walks out to the backyard. Outside, the one-acre lot is a standout feature, offering room to play, garden, entertain, or simply enjoy a level of privacy that is increasingly difficult to find this close to everything. South Dover is prized for its convenient access to both Dover and Portsmouth, with Garrison School nearby and Portsmouth Christian Academy just minutes away. Spend weekends exploring Wagon Hill Farm, Emery Farm, Tendercrop Farm, or launching a boat from Hilton Park. Commuters will appreciate the quick access to Pease Tradeport, Portsmouth, major commuting routes, shopping, dining, and the entire Seacoast. Buyers searching South Dover, should not wait!