Coldwell Banker Home Page
Local Realty Service Provided By: Coldwell Banker Hulsey
Property view
Listing view 2
Listing view 3

221 W Saint Joseph Street, 
Perryville, MO 63775

$560,000


6

Beds


5

Baths


3,143

Sq Ft


Single Family

Active

Listed by

Jacob M. Fish

Kristal Flentge

Edge Realty ERA Powered

Last updated:

January 10, 2026, 04:15 PM

MLS#

25081439

Source:

MO MARIS

About This Home

221 W Saint Joseph Street

Looking for a turn key, fully operational business in the heart of Perryville≠ The Mediterranean House presents a rare opportunity to own a luxury property designed to host unforgettable stays and events. Currently operating as a successful and versatile venue, this property is well suited for use as an Airbnb, bed and breakfast, or a destination for corporate retreats, wellness or yoga getaways, and private events. The home features six beautifully appointed bedrooms, four full bathrooms, and one half bathroom, offering ample accommodations for guests. A commercial grade kitchen equipped with stainless steel appliances is ready to support culinary experiences, from baking and cooking workshops to catered events. All furniture stays, including antique furnishings, bedroom suites, dining room suites, etc. With its flexible layout and elegant setting, The Mediterranean House is ideal for bridal and baby showers, birthday celebrations, intimate gatherings, or larger hosted events. This is a truly turn key business opportunity, ready for immediate operation, offering the space, functionality, and charm to bring a wide range of visions to life.

Home Facts

Single Family

5 Baths

6 Bedrooms

Built in 1910

Price Summary

560,000

$178 per Sq. Ft.

MLS #:

25081439

Last Updated:

January 10, 2026, 04:15 PM


Rooms & Interior

Bedrooms

Total Bedrooms:

6

Bathrooms

Total Bathrooms:

5

Full Bathrooms:

4

Interior

Living Area:

3,143 Sq. Ft.


Structure

Structure

Architectural Style:

Historic

Building Area:

3,143 Sq. Ft.

Year Built:

1910


Lot

Lot Size (Sq. Ft):

16,117


Finances & Disclosures

Finances

Price:

$560,000

Price per Sq. Ft:

$178 per Sq. Ft.

MLS Logo
Copyright 2026 Mid-America Regional Information Systems. All rights reserved. Listings courtesy of Mid-America Regional Information Systems as distributed by MLS GRID

Contact an Agent

Yes, I would like more information. Please use and/or share my information with a Coldwell Banker ® affiliated agent to contact me about my real estate needs. By clicking Contact, I request to be contacted by phone or text message and consent to being contacted by automated means. I understand that my consent to receive calls or texts is not a condition of purchasing any property, goods, or services. Alternatively, I understand that I can access real estate services by email or I can contact the agent myself.

If a Coldwell Banker affiliated agent is not available in the area where I need assistance, I agree to be contacted by a real estate agent affiliated with another brand owned or licensed by Anywhere Real Estate (BHGRE®, CENTURY 21®, Corcoran®, ERA®, or Sotheby's International Realty®). I acknowledge that I have read and agree to the terms of use and privacy notice.

Contact an Agent

Yes, I would like more information. Please use and/or share my information with a Coldwell Banker ® affiliated agent to contact me about my real estate needs. By clicking Contact, I request to be contacted by phone or text message and consent to being contacted by automated means. I understand that my consent to receive calls or texts is not a condition of purchasing any property, goods, or services. Alternatively, I understand that I can access real estate services by email or I can contact the agent myself.

If a Coldwell Banker affiliated agent is not available in the area where I need assistance, I agree to be contacted by a real estate agent affiliated with another brand owned or licensed by Anywhere Real Estate (BHGRE®, CENTURY 21®, Corcoran®, ERA®, or Sotheby's International Realty®). I acknowledge that I have read and agree to the terms of use and privacy notice.