4100 Lancaster Pike, Wilmington, Delaware, a grand, character-rich Wilmington estate that blends historic elegance with modern luxury. Set on nearly half an acre of fenced grounds, this 5,350 sq. ft. colonial masterpiece offers six bedrooms, multiple living and entertaining spaces, and architectural features rarely found today. Vaulted ceilings, original archways, a striking spiral staircase, and multiple fireplaces showcase the home’s timeless craftsmanship, while thoughtful updates deliver the comfort and convenience expected in a luxury residence. At the heart of the home is a gourmet kitchen designed for both everyday living and elevated entertaining, complete with quartz countertops and a stylish black stainless appliance package. Sunlight pours into the adjoining living areas and the inviting sunroom, creating warm spaces that highlight the home’s charm and sophistication. Flexible living arrangements are a standout feature here. With spacious bedrooms, an au pair or in-law suite, and dedicated in-home office space, the home easily supports multi-generational living and modern work-from-home lifestyles. A three-car garage offers exceptional storage and appeals to collectors or car enthusiasts seeking space and security. The location marries convenience with prestige—just minutes from Wilmington and within easy reach of the Baltimore–Philadelphia corridor. Residents enjoy quick access to the upscale boutiques, dining, and everyday amenities of Greenville, Centreville, and Hockessin, making the property especially attractive for out-of-state transferees seeking East Coast accessibility at a stronger value. Currently offered at a competitive price relative to local comparables, 4100 Lancaster Pike presents a rare opportunity to own a distinctive piece of Wilmington’s architectural heritage—one that offers scale, elegance, and versatility for both refined living and memorable entertaining.