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422 21st St, 
Denver, CO 80205

$1,200,000


4

Beds


2

Baths


6,565

Sq Ft


Single Family

Pending

Listed by

Karen Zeile

Kentwood Commercial, LLC.

303-773-3399

Last updated:

May 14, 2026, 07:41 AM

MLS#

6487194

Source:

IRES

About This Home

422 21st St

Located in the heart of Five Points, this unique for-sale offering presents a compelling investment, owner-user, or redevelopment opportunity on a highly visible 6,270 SF corner lot just steps from Downtown Denver, Uptown, and the vibrant Five Points district. The property consists of a well-maintained single-family home and an adjacent office duplex, providing multiple income streams and flexible future potential. The approximately 2,565 SF single-family residence features four bedrooms and two bathrooms and is most recently operated as a successful Airbnb, offering immediate short-term rental income or the option for an owner-user residence. The office duplex is comprised of two office units of approximately 2,000 SF each, both tenant-occupied on month-to-month leases, allowing for steady income with near-term flexibility for repositioning or redevelopment. With its premier corner location, walkability to Denver's central business district, and proximity to restaurants, nightlife, transit, and cultural amenities, this property offers exceptional upside in one of Denver's most dynamic and rapidly evolving neighborhoods.

Home Facts

Single Family

2 Baths

4 Bedrooms

Built in 1886

Price Summary

1,200,000

$182 per Sq. Ft.

MLS #:

6487194

Last Updated:

May 14, 2026, 07:41 AM

Added:

3 month(s) ago


Rooms & Interior

Bedrooms

Total Bedrooms:

4

Bathrooms

Total Bathrooms:

2

Full Bathrooms:

1

Interior

Living Area:

6,565 Sq. Ft.


Structure

Structure

Building Area:

6,565 Sq. Ft.

Year Built:

1886


Lot

Lot Size (Sq. Ft):

6,270


Finances & Disclosures

Finances

Price:

$1,200,000

Price per Sq. Ft:

$182 per Sq. Ft.

Source:IRES
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Contact an Agent

Yes, I would like more information. Please use and/or share my information with a Coldwell Banker ® affiliated agent to contact me about my real estate needs. By clicking Contact, I request to be contacted by phone or text message and consent to being contacted by automated means. I understand that my consent to receive calls or texts is not a condition of purchasing any property, goods, or services. Alternatively, I understand that I can access real estate services by email or I can contact the agent myself.

If a Coldwell Banker affiliated agent is not available in the area where I need assistance, I agree to be contacted by a real estate agent affiliated with another brand owned or licensed by Anywhere Real Estate (BHGRE®, CENTURY 21®, Corcoran®, ERA®, or Sotheby's International Realty®). I acknowledge that I have read and agree to the terms of use and privacy notice.