Rare opportunity, premier vacant lot in Lake Murex, Sanibel Island. One of the largest parcels in sought-after Lake Murex neighborhood, this 1.17-acre lot offers a rare combination of size, privacy and location. Overlooking the untouched 212-acre SCCF Lindblad Preserve, the property delivers sweeping natural views and a serene backdrop that will never be developed. With an impressive 15,834 square feet of impervious coverage and over 18,000 square feet of developed area coverage allowed, this lot offers one of the largest building envelopes on the island and is able to accommodate a large house, resort-style pool and even an attached guest house with no problem. The potential here is unmatched, just look next door, when in 2023, 562 Lake Murex sold for $950,000 for the land alone before being cleared to make way for a luxury new build. In the Little Lake Murex enclave of the popular Lake Murex subdivision, it affords you access to the private HOA tennis and pickleball courts just at end of the street. Tucked away on Sanibel's quiet west end, this property comes with deeded beach access to uncrowded, shell-strewn gulf shores known for their legendary sunsets. Hop on your bike and you're minutes from Sanibel Recreation Center, the new Bit-of-Bailey's General Store, and popular local favorite Rosalita's on Rabbit Road. Whether you're a builder, investor or end-user, this is a standout opportunity to claim one of the island's desirable and build-ready homesites.